gms | German Medical Science

50. Jahrestagung der Deutschen Gesellschaft für Medizinische Informatik, Biometrie und Epidemiologie (gmds)
12. Jahrestagung der Deutschen Arbeitsgemeinschaft für Epidemiologie (dae)

Deutsche Gesellschaft für Medizinische Informatik, Biometrie und Epidemiologie
Deutsche Arbeitsgemeinschaft für Epidemiologie

12. bis 15.09.2005, Freiburg im Breisgau

Overweight and incidence of cancer: results of a large cohort study with more than 145,000 adults in Austria

Meeting Abstract

  • Kilian Rapp - Department of Epidemiology, University of Ulm, Ulm, Germany
  • Jane Schroeder - Department of Epidemiology, University of North Carolina, North Carolina, USA
  • Jochen Klenk - Department of Epidemiology, University of Ulm, Ulm, Germany
  • Susanne Stöhr - Department of Epidemiology, University of Ulm, Ulm, Germany
  • Hanno Ulmer - Department of Medical Statistics, Informatics and Health Economics, Medical University, Innsbruck, Austria
  • Hans Concin - Agency for Preventive and Social Medicine, Bregenz, Austria
  • Günter Diem - Agency for Preventive and Social Medicine, Bregenz, Austria
  • Wilhelm Oberaigner - Cancer Registry of Tyrol, Department of Clinical Epidemiology of the Tyrolean State Hospitals Ltd, Innsbruck, Austria
  • Stephan K. Weiland - Department of Epidemiology, University of Ulm, Ulm, Germany

Deutsche Gesellschaft für Medizinische Informatik, Biometrie und Epidemiologie. Deutsche Arbeitsgemeinschaft für Epidemiologie. 50. Jahrestagung der Deutschen Gesellschaft für Medizinische Informatik, Biometrie und Epidemiologie (gmds), 12. Jahrestagung der Deutschen Arbeitsgemeinschaft für Epidemiologie. Freiburg im Breisgau, 12.-15.09.2005. Düsseldorf, Köln: German Medical Science; 2005. Doc05gmds197

Die elektronische Version dieses Artikels ist vollständig und ist verfügbar unter: http://www.egms.de/de/meetings/gmds2005/05gmds152.shtml

Veröffentlicht: 8. September 2005

© 2005 Rapp et al.
Dieser Artikel ist ein Open Access-Artikel und steht unter den Creative Commons Lizenzbedingungen (http://creativecommons.org/licenses/by-nc-nd/3.0/deed.de). Er darf vervielf&aauml;ltigt, verbreitet und &oauml;ffentlich zug&aauml;nglich gemacht werden, vorausgesetzt dass Autor und Quelle genannt werden.


Gliederung

Text

To investigate the relation of overweight and obesity with the incidence of cancer a population-based cohort of more than 145,000 Austrian adults (67,447 men and 78,484 women) was followed over an average of 10.9 years. Incident cancers (n=6241) were documented by the state cancer registry. Cox proportional-hazards models were calculated adjusting for smoking and occupational group. In men, increases in relative body weight were associated with colon cancer (hazard rate ratio (HR) 2.48; 95% confidence interval (CI): 1.15, 5.39 for body-mass index (BMI) ≥ 35 kg/m2) and pancreatic cancer (HR 2.34, 95% CI: 1.17, 4.66 for BMI > 30 kg/m2) compared to participants with normal weight (BMI 18.5 to 24.9 kg/m2). In women, there was a weak positive association between increasing BMI and all cancers combined, and strong associations with non-Hodgkin’s lymphomas (HR 2.86, 95% CI: 1.49, 5.49 for BMI ≥ 30 kg/m2) and cancers of the uterine corpus (HR 3.93, 95% CI: 2.35, 6.56 for BMI ≥ 35 kg/m2). Incidence of breast cancer was positively associated with high BMI after age 65 years. These findings provide further evidence that overweight is associated with the incidence of several types of cancer in men and women.