Artikel
French Microbiology Laboratories Practices concerning Antibiotic Therapy and Prevention of Antimicrobial Resistance
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Veröffentlicht: | 10. Juli 2012 |
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Gliederung
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Background: HAS promoted guidelines on prevention of bacterial resistance and quality of microbiology labs.
Objectives: Analysis of implementation of guidelines.
Methods: Checklists for organisation and practices of 227 representative hospital labs.
Results: Survey of bacterial resistance was made in 95% of labs with internal quality control (85% of public, 64% of private labs -p = 0.001), evaluation of procedures in 57% of general, 84% of private labs (p = 0.012). A basic service was maintained in 85% of labs. Delay for giving the antibiotic susceptibilities was lower than 36 h in 33% of public , 52% of private labs (p = 0.038). There was a information system in 88% of public, 75% of private labs (p = 0.006), a liaison with the pharmacy in 78% of public, 63% of private labs (p = 0.043). There was an epidemiological surveillance (87%), and an alert system (93%) mostly by computer in public hospitals or by phone in private labs (56%) (p = 0.003). Results on resistance rates were submitted to the committee for the prevention of hospital infection (93%) or of anti-infectives (71%), to the clinical departments in 50% of public, 75% of private hospitals (p = 0.022). Bacterial resistances were compared with antibiotic consumptions in 45% of general, 61% of university, 34% of private hospitals (p = 0.026).
Conclusions: Efforts have to be performed in internal quality procedures and communication about bacterial resistances to the institutional committees and clinical departments.