gms | German Medical Science

15. Jahrestagung der Gesellschaft für Arzneimittelanwendungsforschung und Arzneimittelepidemiologie

Gesellschaft für Arzneimittelforschung und Arzneimittelepidemiologie

20.11. - 21.11.2008, Bonn

Educational Intervention and Monitoring Programme to Improve Physician Reporting of Adverse Drug Reactions (ADRs) in a Primary Care Setting

Verbesserung der UAW Meldungen von niedergelassenen Ärzten durch ein interaktives Schulungskonzept

Meeting Abstract

  • corresponding author Manuela Tabali - Research Institute and Community Hospital Havelhoehe, Berlin, Germany
  • Elke Jeschke - Research Institute and Community Hospital Havelhoehe, Berlin, Germany
  • Angelina Bockelbrink - Institute of Social Medicine, Epidemiology and Health Economics, Charité University Medical Centre, Berlin, Germany
  • Claudia M. Witt - Institute of Social Medicine, Epidemiology and Health Economics, Charité University Medical Centre, Berlin, Germany
  • Stefan N. Willich - Institute of Social Medicine, Epidemiology and Health Economics, Charité University Medical Centre, Berlin, Germany
  • Thomas Ostermann - Chair of Medical Theory and Complementary Medicine, University of Witten/Herdecke, Herdecke, Germany
  • Harald Matthes - Research Institute and Community Hospital Havelhoehe, Berlin, Germany

Gesellschaft für Arzneimittelanwendungsforschung und Arzneimittelepidemiologie e.V. (GAA). 15. Jahrestagung der Gesellschaft für Arzneimittelanwendungsforschung und Arzneimittelepidemiologie. Bonn, 20.-21.11.2008. Düsseldorf: German Medical Science GMS Publishing House; 2008. Doc08gaa15

Die elektronische Version dieses Artikels ist vollständig und ist verfügbar unter: http://www.egms.de/de/meetings/gaa2008/08gaa15.shtml

Veröffentlicht: 6. November 2008

© 2008 Tabali et al.
Dieser Artikel ist ein Open Access-Artikel und steht unter den Creative Commons Lizenzbedingungen (http://creativecommons.org/licenses/by-nc-nd/3.0/deed.de). Er darf vervielf&aauml;ltigt, verbreitet und &oauml;ffentlich zug&aauml;nglich gemacht werden, vorausgesetzt dass Autor und Quelle genannt werden.


Gliederung

Text

Background: Recent studies have shown that adverse drug reactions (ADRs) are underreported. This may be particularly true of ADRs associated with complementary and alternative medicine (CAM). Data on CAM-related ADRs, however, are sparse.

Objective: To evaluate the impact of an educational intervention and monitoring programme designed to improve physician reporting of ADRs in a primary care setting.

Design and participants: A prospective multicentre study with 38 primary care practitioners specialized in CAM was conducted from January 2004 through June 2007. All physicians received face-to-face training to assist them in classifying and reporting ADRs. The study centre monitored the quantity and quality of ADR reports and analysed the results.

Results: A total of 404 ADRs were reported during the study period. An initial 148% increase (P=0.001) in the number of ADR reports was observed after the educational intervention. However, this increase was temporary. The completeness of the ADR reports increased from 79.3% before to 91.6% after the intervention. The completeness of the item for classifying ADRs as serious or non-serious increased significantly (P<0.001) after the educational intervention. The quality of ADR reports, as measured by the correlation between physician and study centre assessments of causality, increased from kappa 0.15 (95% CI: 0.08; 0.29) before to 0.43 (95% CI: 0.23; 0.63) after the intervention.

Conclusion: The results of the present study demonstrate that an educational intervention can increase physician awareness of ADRs. Participating physicians were able to incorporate the knowledge they had gained from face-to-face training into their daily clinical practice. However, the effects of the intervention were temporary. Further research is needed to determine whether extended or continuous educational measures might lead to more durable improvements in ADR reporting rates.