gms | German Medical Science

104. Jahrestagung der Deutschen Ophthalmologischen Gesellschaft e. V. (DOG)

21. - 24.09.2006, Berlin

Relationship between trace elements and retinopathy of prematurity

Meeting Abstract

Suche in Medline nach

  • H. Yang - Department of Ophthalmology, Tongji Hospital, Affiliated Tongji Medical College, Hua Zhong University of Science and Technology, Wuhan, China
  • Y. Ding - Department of Ophthalmology, Tongji Hospital, Affiliated Tongji Medical College, Hua Zhong University of Science and Technology, Wuhan, China
  • L. Chen - Department of Ophthalmology, Tongji Hospital, Affiliated Tongji Medical College, Hua Zhong University of Science and Technology, Wuhan, China

Deutsche Ophthalmologische Gesellschaft e.V.. 104. Jahrestagung der Deutschen Ophthalmologischen Gesellschaft (DOG). Berlin, 21.-24.09.2006. Düsseldorf, Köln: German Medical Science; 2006. Doc06dogP246

Die elektronische Version dieses Artikels ist vollständig und ist verfügbar unter: http://www.egms.de/de/meetings/dog2006/06dog768.shtml

Veröffentlicht: 18. September 2006

© 2006 Yang et al.
Dieser Artikel ist ein Open Access-Artikel und steht unter den Creative Commons Lizenzbedingungen (http://creativecommons.org/licenses/by-nc-nd/3.0/deed.de). Er darf vervielf&aauml;ltigt, verbreitet und &oauml;ffentlich zug&aauml;nglich gemacht werden, vorausgesetzt dass Autor und Quelle genannt werden.


Gliederung

Text

Objective

To observe the metabolism change of trace elements in the blood of preterm infants and infants who suffer from retinopathy of prematurity.

Methods

We selected 30 preterm infants who had potential high risk factors for ROP as the study group and 18 normal infants as the control group. We measured the content of trace elements (such as Mg, Cu, Zn, Mn, Se) in their serum by spectrophotometry.

Results

The contents of Zn, Cu and Se in the serum of the 30 patients were (0.75±0.22) mg/l, (0.41±0.20) mg/l and (134.07±71.57)×10-3 mg/l, respectively, but (0.55±0.12) mg/l, (0.65±0.194) mg/l and (202.92±44.71)×10-3 mg/l in the 18 control subjects. The contents of Cu and Se are significantly lower in the study group than in the control group (P<0.01), while the content of Zn in patients serum is significantly higher (P<0.01). And there are similar result between the infants that suffer from ROP and the control group (P<0.01). The difference of Mn and Mg content in the serum of the two groups was not statistically significant.

Conclusions

The contents of Cu and Se in preterm infants who had a high risk of ROP are lower than those of the control group. Among them the contents of Cu and Se in the ROP infants are also much lower while the content of Zn is much higher. This may play a role for the development of ROP.