gms | German Medical Science

104. Jahrestagung der Deutschen Ophthalmologischen Gesellschaft e. V. (DOG)

21. - 24.09.2006, Berlin

Subretinal active visual prothesis in blind patients: The intraorbital and facial surgical procedure

Subdermale und intraorbitale Leitungszuführung zum transchoroidal implantierten subretinalen Implantat

Meeting Abstract

  • D. Besch - Centre for Ophthalmology, Tübingen
  • D. Gülicher - Department of Oral and Maxillofacial Surgery, University Tübingen
  • S. Reinert - Department of Oral and Maxillofacial Surgery, University Tübingen
  • H. Sachs - University Eye Hospital, Regensburg
  • K.-U. Bartz-Schmidt - Centre for Ophthalmology, Tübingen
  • E. Zrenner - Centre for Ophthalmology, Tübingen
  • F. Gekeler - Centre for Ophthalmology, Tübingen

Deutsche Ophthalmologische Gesellschaft e.V.. 104. Jahrestagung der Deutschen Ophthalmologischen Gesellschaft (DOG). Berlin, 21.-24.09.2006. Düsseldorf, Köln: German Medical Science; 2006. Doc06dogSA.06.05

Die elektronische Version dieses Artikels ist vollständig und ist verfügbar unter:

Veröffentlicht: 18. September 2006

© 2006 Besch et al.
Dieser Artikel ist ein Open Access-Artikel und steht unter den Creative Commons Lizenzbedingungen ( Er darf vervielf&aauml;ltigt, verbreitet und &oauml;ffentlich zug&aauml;nglich gemacht werden, vorausgesetzt dass Autor und Quelle genannt werden.




The subretinally implanted multi-electrode array and its external energy supply via a retroauricular plug requires an extraocular surgical procedure connecting the retroauricular access with the transchoroidal implanted chip via anterior orbit. A safe fixation of the implant in intraorbital and facial structures is mandatory for a successful chronic implantation in humans.


Up to now the device has been chronically implanted into 4 eyes of blind retinitis pigmentosa patients. Chip and stimulation electrodes are positioned on a small subretinal polyimide foil powered via a subretinal transchoroidal, retroauricular subdermal line ending in a radio-controlled, battery-driven receiver-box. The device was implanted into the subretinal space next to the foveal rim of two blind retinitis pigmentosa patients (see Sachs et al. 2006). The subretinal polyimide strip leaves the eye bulb between equator and pars plana through the choroid and a scleral flap. The foil carries connection lanes to a silicone cable that was positioned intraorbitally below the upper lid up to the lateral orbit bone and underneath the M. temporalis to the retroauricular access. The foil and silicone cable were stabilized by scleral and orbital rim fixation patches as well as a retroauricular metal clamp with bone screws. Explantation was scheduled after 4 weeks.


The implantation was successfully performed in all patients and the device was well tolerated without severe adverse events during the observation period. During the first few days after surgery swelling of the upper lid and mild tension during eye movements with conjunctival chemosis occurred. Patients did not report any irritation from the retroauricular plug. After one week the situation was stable and chronic stimulation could be successfully performed. According to study plan, implants were removed after 4 weeks. One patient decided to keep the implant. 6 months after implantation the intraorbital and facial device is still stable without any irritation in spite of the chronic foreign body and the retroauricular transdermal access for the silicone cable.


Our findings demonstrate for the first time the feasibility of a new surgical procedure for highly safe and controlled implantation of complex devices with subretinal and extra-ocular parts in blind humans. The access from the sclera via a loop to the lateral orbital rim with a transdermal cable behind the ear proved to be stable for more than 6 months.