gms | German Medical Science

104. Jahrestagung der Deutschen Ophthalmologischen Gesellschaft e. V. (DOG)

21. - 24.09.2006, Berlin

Needling revision with subconjunctival 5-Fluorouracil in failing filtering blebs after trabeculectomy

Meeting Abstract

Suche in Medline nach

  • Z. Mandic - University Department of Ophthalmology, University Hospital "Sestre milosrdnice"
  • M. Geber-Zoric - University Department of Ophthalmology, University Hospital "Sestre milosrdnice"
  • G. Bencic - University Department of Ophthalmology, University Hospital "Sestre milosrdnice"

Deutsche Ophthalmologische Gesellschaft e.V.. 104. Jahrestagung der Deutschen Ophthalmologischen Gesellschaft (DOG). Berlin, 21.-24.09.2006. Düsseldorf, Köln: German Medical Science; 2006. Doc06dogDO.06.08

Die elektronische Version dieses Artikels ist vollständig und ist verfügbar unter: http://www.egms.de/de/meetings/dog2006/06dog048.shtml

Veröffentlicht: 18. September 2006

© 2006 Mandic et al.
Dieser Artikel ist ein Open Access-Artikel und steht unter den Creative Commons Lizenzbedingungen (http://creativecommons.org/licenses/by-nc-nd/3.0/deed.de). Er darf vervielf&aauml;ltigt, verbreitet und &oauml;ffentlich zug&aauml;nglich gemacht werden, vorausgesetzt dass Autor und Quelle genannt werden.


Gliederung

Text

Objective

To evaluate a surgical technique to revise a failed filtering bleb, after trabeculectomy using subconjunctival 5-FU.

Methods

We reviewed retrospectively 24 consecutive eyes with bleb revisions. All eyes had previously functioning filtering bleb with inadequately controlled intraocular pressures (IOP) prior to the revisions. The procedure was usually performed as a clinic procedure, using a 27 G needle to lyse subconjunctival fibrosis and episcleral scar tissue binding down and elevate the scleral flap. 5-Fluorouracil (0,1 ml: 50mg/ml) was infiltrated around the bleb. The main outcome measures were IOP, number of glaucoma medications, and complications.

Results

The mean follow-up time was 10,5±7,3 months (range 6-15 months). Intraocular pressure (IOP) decreased from 26,4±4,6 mmHg (range 18-31 mmHg) to 16,3±4,8 mmHg (range 8-28 mmHg). Twelve eyes achieved success, defined as IOP same or less than 18 mmHg without medications. Eleven eyes achieved qualified success (IOP same or less than 18 mmHg with antiglaucoma medications), and three eyes were classified as failures. Complications developed in 4 eyes (corneal epithelial defect, subconjunctival haemorrhage, temporary conjunctival leak and bullous keratopathy).

Conclusions

These data suggest that bleb needling with 5-FU is a safe and effective method by which a significant number of failed filtration bleb can be rescued from failure.