gms | German Medical Science

102. Jahrestagung der DOG

Deutsche Ophthalmologische Gesellschaft e. V.

23. bis 26.09.2004, Berlin

Influence of posture on the perfusion of the optic nerve head

Meeting Abstract

  • corresponding author P. Galambos - Universitätsklinikum Hamburg-Eppendorf, Glaukomlabor, Hamburg
  • J. Vafiadis - Universitätsklinikum Hamburg-Eppendorf, Glaukomlabor, Hamburg
  • L. Wagenfeld - Universitätsklinikum Hamburg-Eppendorf, Glaukomlabor, Hamburg
  • E. T. Matthiessen - Universitätsklinikum Hamburg-Eppendorf, Glaukomlabor, Hamburg
  • G. Richard - Universitätsklinikum Hamburg-Eppendorf, Glaukomlabor, Hamburg
  • M. Klemm - Universitätsklinikum Hamburg-Eppendorf, Glaukomlabor, Hamburg
  • O. Zeitz - Universitätsklinikum Hamburg-Eppendorf, Glaukomlabor, Hamburg

Evidenzbasierte Medizin - Anspruch und Wirklichkeit. 102. Jahrestagung der Deutschen Ophthalmologischen Gesellschaft. Berlin, 23.-26.09.2004. Düsseldorf, Köln: German Medical Science; 2004. Doc04dogP 086

Die elektronische Version dieses Artikels ist vollständig und ist verfügbar unter: http://www.egms.de/de/meetings/dog2004/04dog577.shtml

Veröffentlicht: 22. September 2004

© 2004 Galambos et al.
Dieser Artikel ist ein Open Access-Artikel und steht unter den Creative Commons Lizenzbedingungen (http://creativecommons.org/licenses/by-nc-nd/3.0/deed.de). Er darf vervielf&aauml;ltigt, verbreitet und &oauml;ffentlich zug&aauml;nglich gemacht werden, vorausgesetzt dass Autor und Quelle genannt werden.


Gliederung

Text

Objective

An altered autoregulation of the optic nerve head perfusion is being discussed as a possible pathogenic factor in normal tension glaucoma. The aim of the present study was to evaluate the influence of a change in body posture on the microcirculation of the optic nerve head in patients with high and normal tension glaucoma (HTG and NTG) controlling for the systemic blood pressure.

Methods

Peak systolic blood flow velocity (PSV) and enddiastolic velocity (EDV) in the short posterior ciliary artery supplying the optic nerve head were measured in a sitting, supine and 30°-upright-position with Color Doppler Imaging (Siemens Elegra, 7.5 MHz) and evaluated statistically. Before each examination systolic and diastolic blood pressures were taken.

Results

In the NTG-group PSV was 9.0±0.8cms-1 in the sitting position. It increased to 11.5±1.1cms-1 in the supine and 11.9±0.6cms-1 in the 30°-position. In the HTG-group PSV changed from 8.2±0.7cms-1 (sitting) to 11.8±1.3cms-1 (supine) and 11.7±1.4cms-1 (30°-position). EDV in the NTG-group was 2.0±0.2cms-1 in the sitting, 3.8±0.4cms-1 in supine and 3.7±0.4cms-1 in the 30°-position. In the HTG-group the EDV increased from 1.9±0.2cms-1 (sitting) to 3.4±0.5cms-1 (supine) and 3.5±0.5cms-1 (30°-position). The increase in PSV and EDV from the sitting to the supine and 30°-position was statistically significant in both groups (p<0.05; n=13 NTG-group; n=17 HTG-group) and independent of the systemic blood pressure (no increase in the systolic or diastolic blood pressure with change of posture from sitting to supine or 30°-position). No difference was observed in this study between HTG and NTG patients.

Conclusions

In HTG- and NTG-patients the local perfusion of the optic nerve head is significantly increased after posture change from the sitting to the supine and 30°-position independent of the systemic blood pressure.