gms | German Medical Science

102. Jahrestagung der DOG

Deutsche Ophthalmologische Gesellschaft e. V.

23. bis 26.09.2004, Berlin

Surgical peeling of idiopathic epiretinal membrane with and without Indocyanine-green (ICG): a retrospective and prospective clinical study

Meeting Abstract

  • corresponding author P. Saikia - Dept. of Ophthalmology, Regensburg University
  • J. Hillenkamp - Dept. of Ophthalmology, Regensburg University
  • F. Gora - Dept. of Ophthalmology, Regensburg University
  • H. G. Sachs - Dept. of Ophthalmology, Regensburg University
  • C. P. Lohmann - Dept. of Ophthalmology, Regensburg University
  • V. P. Gabel - Dept. of Ophthalmology, Regensburg University

Evidenzbasierte Medizin - Anspruch und Wirklichkeit. 102. Jahrestagung der Deutschen Ophthalmologischen Gesellschaft. Berlin, 23.-26.09.2004. Düsseldorf, Köln: German Medical Science; 2004. Doc04dogSO.01.15

Die elektronische Version dieses Artikels ist vollständig und ist verfügbar unter: http://www.egms.de/de/meetings/dog2004/04dog417.shtml

Veröffentlicht: 22. September 2004

© 2004 Saikia et al.
Dieser Artikel ist ein Open Access-Artikel und steht unter den Creative Commons Lizenzbedingungen (http://creativecommons.org/licenses/by-nc-nd/3.0/deed.de). Er darf vervielf&aauml;ltigt, verbreitet und &oauml;ffentlich zug&aauml;nglich gemacht werden, vorausgesetzt dass Autor und Quelle genannt werden.


Gliederung

Text

Objective

To investigate macular function and morphology after peeling of idiopathic epiretinal membrane (IEM) with and without assistance of ICG: a retrospective and prospective clinical study.

Methods

In the retrospective arm a total of 39 patients, 23 female and 16 male, mean age 67 years, and in the ongoing prospective group a total of 10 patients, 8 female and 2 male, mean age 68 years, were included. All patients underwent standard pars-plana-victrectomy with removal of epiretinal membrane. In the retrospective arm, 20 patients were operated with assistance of ICG 0,1% dissolved in glucose 5% and 19 patients without use of ICG. Post-op follow-up was 1-92 months (mean 15.5 months). In the prospective arm patients were randomized to treatment either with or without ICG. Post op follow-up was 3 - 6 months. Functional outcome was assessed with best corrected visual acuity (BCVA), 10° and 30° automated perimetry (Heidelberg visual field analyzer, HFA) and Goldmann kinetic perimetry. Macular morphology was assessed with optical coherence tomography (OCT) and stereoscopic biomicroscopy.

Results

In the retrospective arm BCVA improved in 28 patients, remained unchanged in 8 patients and decreased in 3 patients. Change in BCVA was statistically not different between patients operated with ICG and without ICG. Mean BCVA in patients operated with ICG improved from 0.37±0.16(SD) to 0.6±0.26(SD). Mean BCVA in patients operated without ICG improved from 0.35±0.1(SD) to 0.6±0.24(SD). Visual field defects were detected in one patient with ICG and in three patients without ICG. Stereoscopic biomicroscopy and OCT showed a decrease of macular edema in most patients.

Conclusions

The functional and morphological results of this ongoing study show that removal of IEM with or without assistance of ICG improves visual function and reduces macular edema in most patients. Adverse effects of ICG were not observed but further investigation in our ongoing prospective study is currently being undertaken.