gms | German Medical Science

102. Jahrestagung der DOG

Deutsche Ophthalmologische Gesellschaft e. V.

23. bis 26.09.2004, Berlin

Effect of IOLs with different surface structure on lens epithelial cells (LEC) in vitro on human capsular bag model

Meeting Abstract

  • corresponding author N. Torun - Charité, Clinic of Ophthalmology, University School of Medicine Berlin, Campus Virchow Klinikum
  • N. Pahms - Charité, Clinic of Ophthalmology, University School of Medicine Berlin, Campus Virchow Klinikum
  • A. Porstmann - Charité, Clinic of Ophthalmology, University School of Medicine Berlin, Campus Virchow Klinikum
  • C. Hartmann - Charité, Clinic of Ophthalmology, University School of Medicine Berlin, Campus Virchow Klinikum
  • A. Liekfeld - Charité, Clinic of Ophthalmology, University School of Medicine Berlin, Campus Virchow Klinikum

Evidenzbasierte Medizin - Anspruch und Wirklichkeit. 102. Jahrestagung der Deutschen Ophthalmologischen Gesellschaft. Berlin, 23.-26.09.2004. Düsseldorf, Köln: German Medical Science; 2004. Doc04dogDO.05.06

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Veröffentlicht: 22. September 2004

© 2004 Torun et al.
Dieser Artikel ist ein Open Access-Artikel und steht unter den Creative Commons Lizenzbedingungen (http://creativecommons.org/licenses/by-nc-nd/3.0/deed.de). Er darf vervielf&aauml;ltigt, verbreitet und &oauml;ffentlich zug&aauml;nglich gemacht werden, vorausgesetzt dass Autor und Quelle genannt werden.


Gliederung

Text

Objective

To investigate the effect of intraocular lenses (IOL) with different surface structure on lens epithelial cells (LEC) in vitro on human capsular bags.

Methods

Sham cataract surgery, including IOL-into-the-bag-implantation, was performed on 8 pair of donor eyes after removal of the cornea. The capsular bag including the IOL was removed, pinned on a culture dish, covered with medium, and incubated. In each pair of donor eyes, the two different Silicone-IOLs to be compared, were implanted individually into capsular bags. One eye was assigned to receive a IOL with Fresnel rim structure (Acrisil-73N AL) and the other eye, an IOL without a Fresnel rim structure (Acrisil-73N OM). The time required for complete coverage of the posterior capsule by a confluent monolayer of LEC was documented.

Results

Complete LEC coverage of the posterior capsule occurred between 9 days (Acrisil-73N AL) and after more than 19 days (Acrisil-73N OM). Mean time for total LEC coverage on the posterior capsule was 14.25 (+2.8) days in the capsular bag group with the Acrisil-73N AL implanted. For the Acrisil-73N OM group it was 11.5 (+1.5) days.

Conclusions

The Acrisil-73N AL was associated with a later complete cell coverage of the posterior capsule than the Acrisil-73N OM.