gms | German Medical Science

102. Jahrestagung der DOG

Deutsche Ophthalmologische Gesellschaft e. V.

23. bis 26.09.2004, Berlin

Selective retina therapy (SRT) and optical coherence tomography in patients with central serous retinopathy

Meeting Abstract

  • corresponding author H. Elsner - Dept of Ophthalmology, Campus Lübeck, Universitätsklinikum Schleswig-Holstein, Lübeck
  • E. Pörksen - Dept of Ophthalmology, Campus Lübeck, Universitätsklinikum Schleswig-Holstein, Lübeck
  • C. Klatt - Dept of Ophthalmology, Campus Kiel, Universitätsklinikum Schleswig-Holstein, Lübeck
  • D. Theisen-Kunde - Medical Laser Center Lübeck, Lübeck
  • H. Laqua - Dept of Ophthalmology, Campus Lübeck, Universitätsklinikum Schleswig-Holstein, Lübeck
  • J. Roider - Dept of Ophthalmology, Campus Kiel, Universitätsklinikum Schleswig-Holstein, Lübeck

Evidenzbasierte Medizin - Anspruch und Wirklichkeit. 102. Jahrestagung der Deutschen Ophthalmologischen Gesellschaft. Berlin, 23.-26.09.2004. Düsseldorf, Köln: German Medical Science; 2004. Doc04dogDO.03.01

Die elektronische Version dieses Artikels ist vollständig und ist verfügbar unter: http://www.egms.de/de/meetings/dog2004/04dog018.shtml

Veröffentlicht: 22. September 2004

© 2004 Elsner et al.
Dieser Artikel ist ein Open Access-Artikel und steht unter den Creative Commons Lizenzbedingungen (http://creativecommons.org/licenses/by-nc-nd/3.0/deed.de). Er darf vervielf&aauml;ltigt, verbreitet und &oauml;ffentlich zug&aauml;nglich gemacht werden, vorausgesetzt dass Autor und Quelle genannt werden.


Gliederung

Text

Objective

Selective retina therapy (SRT) is a new innovative laser technology, which is capable of selectively damaging the retinal pigment epithelium (RPE) and sparing the photoreceptors.This therapeutical concept seems to be ideal to treat patients with central serous retinopathy (CSR). Optical coherence tomography (OCT) is used to analyze the specific RPE changes in patients with (CSR) before and after SRT.

Methods

7 patients with active CSR (history of 3 months) were examined and treated with SRT. Preoperative examinations included: Visual acuity (VA), fluorescein angiography, Zeiss OCT III. SRT: laser expositions to the RPE leak (Nd:YLF-Laser, 527 nm, pulsed, pulse length 1,7μs, 100 Hz, energy 5-40μJ). Follow-up visits after 4 weeks and 3 months.

Results

VA measured preoperatively in the median 20/50, after 4 week 20/36 and after 3 months VA further increased to 20/20. All patients presented initially with an angiographically visible RPE leak typical for CSR. After 4 weeks and 3 months all patients showed no more angiographical leakage activity. On OCT all patients demonstrated substantial subretinal fluid extending under the fovea. In four patients the site of RPE leakage was identified as a small pigment epithelial detachment. After 4 weeks 5 of 7 patients showed a complete resolution of subretinal fluid with foveal reattachment. In the other 2 patients we saw a copmlete resorbtion of subretinal fluid after 3 months. In 2 of the 4 patients the PED resolved after 3 months showing a thickened RPE band, in the other 2 patients the PED persisted.

Conclusions

SRT is a safe and efficiant therapy for patient with active CSR, especially if the site of RPE leakage is located close to the fovea. OCT is ideal to visualize the pathology in CSR and showes RPE remodeling processes after SRT. The results point into the direction that SRT leads to a restauration of the outer blood retinal barrier.