gms | German Medical Science

102. Jahrestagung der DOG

Deutsche Ophthalmologische Gesellschaft e. V.

23. bis 26.09.2004, Berlin

Correlation of OCT with fluorescein and ICG angiographical characteristics in patients with exudative AMD

Meeting Abstract

  • corresponding author A. Meister - Department of Ophthalmology, St. Franziskus Hospital, Muenster
  • C. Gerth - Department of Ophthalmology, St. Franziskus Hospital, Muenster
  • G. Spital - Department of Ophthalmology, St. Franziskus Hospital, Muenster
  • M. Trieschmann - Department of Ophthalmology, St. Franziskus Hospital, Muenster
  • A. Lommatzsch - Department of Ophthalmology, St. Franziskus Hospital, Muenster
  • D. Pauleikhoff - Department of Ophthalmology, St. Franziskus Hospital, Muenster

Evidenzbasierte Medizin - Anspruch und Wirklichkeit. 102. Jahrestagung der Deutschen Ophthalmologischen Gesellschaft. Berlin, 23.-26.09.2004. Düsseldorf, Köln: German Medical Science; 2004. Doc04dogDO.01.09

Die elektronische Version dieses Artikels ist vollständig und ist verfügbar unter: http://www.egms.de/de/meetings/dog2004/04dog009.shtml

Veröffentlicht: 22. September 2004

© 2004 Meister et al.
Dieser Artikel ist ein Open Access-Artikel und steht unter den Creative Commons Lizenzbedingungen (http://creativecommons.org/licenses/by-nc-nd/3.0/deed.de). Er darf vervielf&aauml;ltigt, verbreitet und &oauml;ffentlich zug&aauml;nglich gemacht werden, vorausgesetzt dass Autor und Quelle genannt werden.


Gliederung

Text

Objective

Morphological subtypes of exudative age-related macular degeneration (AMD) were differentiated by fluorescein (FA) and ICG angiography. These findings were correlated with optical coherence tomography (OCT) to analyze the specific morphology of these exudative AMD subtypes.

Methods

Exudative AMD was differentiated by FA and ICG (HRA) in 150 patients: classic choroidal neovascularisation (CNV) 40 pat., occult CNV 40 pat., occult CNV with serous pigment epithelium detachment (PED) 26 pat., Drusen-PED 23 pat., RAP-PED 11 pat., PCV-PED 5 pat., RIP-PED 5 pat.. The OCT (Humphrey System) characteristics in each group were analyzed systematically.

Results

Classic CNV demonstrated an increased reflectivity and thickening of the RPE band in the subretinal direction with well defined borders and fluid accumulation in the subretinal space consistent with a distinct extension of the CNV predominantly in the subretinal space. In contrast, occult CNV showed a less confined increased reflectivity mostly underneath the RPE. Occult CNV with serous PED showed an increased reflectivity in the sub-RPE space on the border (CNV) with a focal detachment of the RPE band over an optically clear space. Drusen-PED were characterized by increased reflectivity in the sub-RPE space but normal RPE band. PED associated with RAP showed an increased reflectivity of the RPE band on top of the PED, while PCV-PED revealed a small increased reflectivity in the choroid under the PED. RIP-PED were characterized with a thickened increased reflectivity in the middle of the PED.

Conclusions

The OCT characteristics could be differentiated in respect to different FA and ICG classifications and are consistent with the histopathological concepts of the different exudative AMD subtypes. Morphology assessed with OCT as well as FA and ICG angiography is an efficient in vivo tool in patients with exudative AMD.