gms | German Medical Science

65. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie (DGNC)

Deutsche Gesellschaft für Neurochirurgie (DGNC) e. V.

11. - 14. Mai 2014, Dresden

Gamma knife radiosurgery for AVM’s: A clinical series of 199 patients

Meeting Abstract

  • Selcuk Peker - Acibadem University School of Medicine, Department of Neurosurgery, Istanbul, Turkey
  • Ipek Arslan Kabalay - Gaziosmanpasa University School of Medicine, Department of Radiation Oncology, Tokat, Turkey
  • Evrim K. Tezcanli - Acibadem University School of Medicine, Department of Radiation Oncology, Istanbul, Turkey
  • K. Meric Sengoz - Acibadem University School of Medicine, Department of Radiation Oncology, Istanbul, Turkey
  • M. Olcay Cizmeli - Acibadem University School of Medicine, Department of Radiology, Istanbul, Turkey
  • M. Necmettin Pamir - Acibadem University School of Medicine, Department of Neurosurgery, Istanbul, Turkey

Deutsche Gesellschaft für Neurochirurgie. 65. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie (DGNC). Dresden, 11.-14.05.2014. Düsseldorf: German Medical Science GMS Publishing House; 2014. DocMO.20.02

doi: 10.3205/14dgnc114, urn:nbn:de:0183-14dgnc1140

Veröffentlicht: 13. Mai 2014

© 2014 Peker et al.
Dieser Artikel ist ein Open Access-Artikel und steht unter den Creative Commons Lizenzbedingungen (http://creativecommons.org/licenses/by-nc-nd/3.0/deed.de). Er darf vervielfältigt, verbreitet und öffentlich zugänglich gemacht werden, vorausgesetzt dass Autor und Quelle genannt werden.


Gliederung

Text

Objective: The aim of this study was to evaluate outcomes following gamma knife radiosurgery (GKRS) for arteriovenous malformations (AVMs).

Method: The present series included 199 patients (3-74 years of age) who underwent GKRS for cerebral AVMs between September 2005 and November 2010. In 43% of the patients the main symptom was hemorrhage. The median AVM volume was 4.9 cm3, and the median marginal dose was 22 Gy. All patients continued to have follow-up for more than 60 months with serial magnetic resonance images (MRIs)/angiograms.

Results: Follow-up radiological examinations confirmed complete obliteration in 140 patients (70%). Postradiosurgical hemorrhage was observed in 6 (3%) patients. Adverse radiation effects were seen in 3 patients (1.5%). The Spetzler-Martin grade, marginal dosis, volume and Pollock-Flickinger grade were found to be reliable predictors for total obliteration.

Conclusions: The results of the present study demonstrated a high total obliteration rate with low complications can be achievable in the GKRS treatment of AVM’s.