gms | German Medical Science

63. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie (DGNC)
Joint Meeting mit der Japanischen Gesellschaft für Neurochirurgie (JNS)

Deutsche Gesellschaft für Neurochirurgie (DGNC) e. V.

13. - 16. Juni 2012, Leipzig

Peripheral nerve stimulation (PNS) – extended therapeutic options with complex stimulation systems – case series

Meeting Abstract

Suche in Medline nach

  • J. Perrin - Neurochirurgische Klinik, Abteilung Neuromodulation, Universitätsklinikum Düsseldorf
  • C. Wille - Neurochirurgische Klinik, Abteilung Neuromodulation, Universitätsklinikum Düsseldorf
  • J. Vesper - Neurochirurgische Klinik, Abteilung Neuromodulation, Universitätsklinikum Düsseldorf

Deutsche Gesellschaft für Neurochirurgie. Japanische Gesellschaft für Neurochirurgie. 63. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie (DGNC), Joint Meeting mit der Japanischen Gesellschaft für Neurochirurgie (JNS). Leipzig, 13.-16.06.2012. Düsseldorf: German Medical Science GMS Publishing House; 2012. DocP 031

DOI: 10.3205/12dgnc418, URN: urn:nbn:de:0183-12dgnc4182

Veröffentlicht: 4. Juni 2012

© 2012 Perrin et al.
Dieser Artikel ist ein Open Access-Artikel und steht unter den Creative Commons Lizenzbedingungen (http://creativecommons.org/licenses/by-nc-nd/3.0/deed.de). Er darf vervielfältigt, verbreitet und öffentlich zugänglich gemacht werden, vorausgesetzt dass Autor und Quelle genannt werden.


Gliederung

Text

Objective: Peripheral nerve stimulation (PNS) delivers targeted relief from neuropathic pain in peripheral nerve disorders. Traditional approaches promote placement of one electrode in proximity to the nerve lesion. Durability of hardware, limited therapeutic range and motor side effects are common problems often prompting multiple revisions. In SCS it is an accepted development to improve stimulation results by more complex electrode designs or combinations of electrodes. We demonstrate PNS of the proximal sciatic nerve with two or more electrodes in patients with neuropathic pain of different origins refractory to conservative treatment or other neuromodulation approaches.

Methods: Four patients (2 male/2 female) with neuropathic foot or leg pain due to extensive trauma (2), compartment syndrome (1) or amputation (1) underwent electrode placement at the proximal portion of the sciatic nerve over a dorsal approach. Electrodes were placed adjacent to each other to allow a thorough coverage. Effects, thresholds and therapeutic range for single and combined stimulation were assessed during trial period and 3 months after stimulator placement.

Results: In all patients combined stimulation was superior to single electrode stimulation regarding therapeutic effect and range. Mean paresthesia coverage was 85% for combined vs. 45% for single stimulation. VAS improvement at mean 68% was recorded at 12-month follow-up. Median follow-up is 15 months.

Conclusions: Our preliminary data suggest improved PNS results with more complex stimulation setups. The possibility to achieve stimulation coverage and selectiveness more independently from anatomic considerations may help to avoid complications, surgical revisions und improve therapeutic success.