Artikel
Transsphenoidal surgery for pituitary adenoma and craniopharyngioma with endoscope assistance, special emphasis on tips and how to avoid complications
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Veröffentlicht: | 4. Juni 2012 |
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Gliederung
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Objective: We have no objection to the doctrine that micro-neurosurgery under the operating microscope is crucial to the basis of neurosurgery. But in recent years, endoscopic micro-neurosurgery has been spreading dramatically and very speedily. We have also steadily expanded the indication for the endoscopic approach with the microscope in a safe and accurate fashion. We compared the normalization rate of growth hormone and IGF-1 between the microscope era (1995–1999, n = 32) and the era of combined use (2000–2010, n = 93).
Methods: We analyzed the nadir value of GH with OGTT and IGF-1 before and after TSS between both eras in acromegaly patients from 1995 to 1999, who underwent microscopic surgery and from 2000 to 2010 who underwent combined use surgery.
Results: The cure rate using the Knosp grade 0 to 2 was 83% in the microscope era and 92% in the combined use era, respectively. The cure rate using Knosp grade 3 to 4 was 13% and 24%, respectively. In all periods, it was 66% and 76%, respectively. According to IGF-1 normalization, in total, it was 56% and 67%, respectively. In this presentation, we will show our present status of microscopic and endoscopic removal of pituitary adenoma and craniopharyngioma via the transnasal route. We would also like to emphasize the benefit of combined use, tips and tactics and how to avoid complications using this approach.
Conclusions: In conclusion, the combined use of microscope and endoscope provide good surgical results with a higher cure rate of pituitary adenoma and craniopharyngioma.