gms | German Medical Science

62. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie (DGNC)
Joint Meeting mit der Polnischen Gesellschaft für Neurochirurgen (PNCH)

Deutsche Gesellschaft für Neurochirurgie (DGNC) e. V.

07. - 11. Mai 2011, Hamburg

Early CT perfusion measurement after aneurysmal subarachnoid hemorrhage as a possible predictor for the outcome?

Meeting Abstract

  • H.J. Heiroth - Klinik für Neurochirurgie, Heinrich-Heine-Universität, Düsseldorf
  • M. Kamp - Klinik für Neurochirurgie, Heinrich-Heine-Universität, Düsseldorf
  • N. Etminan - Klinik für Neurochirurgie, Heinrich-Heine-Universität, Düsseldorf
  • B. Turowski - Institut für Radiologie, Heinrich-Heine-Universität, Düsseldorf
  • H.J. Steiger - Klinik für Neurochirurgie, Heinrich-Heine-Universität, Düsseldorf
  • D. Hänggi - Klinik für Neurochirurgie, Heinrich-Heine-Universität, Düsseldorf

Deutsche Gesellschaft für Neurochirurgie. Polnische Gesellschaft für Neurochirurgen. 62. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie (DGNC), Joint Meeting mit der Polnischen Gesellschaft für Neurochirurgen (PNCH). Hamburg, 07.-11.05.2011. Düsseldorf: German Medical Science GMS Publishing House; 2011. DocDI.10.06

DOI: 10.3205/11dgnc170, URN: urn:nbn:de:0183-11dgnc1708

Veröffentlicht: 28. April 2011

© 2011 Heiroth et al.
Dieser Artikel ist ein Open Access-Artikel und steht unter den Creative Commons Lizenzbedingungen (http://creativecommons.org/licenses/by-nc-nd/3.0/deed.de). Er darf vervielfältigt, verbreitet und öffentlich zugänglich gemacht werden, vorausgesetzt dass Autor und Quelle genannt werden.


Gliederung

Text

Objective: The outcome of patients after aneurysmal subarachnoid hemorrhage (SAH) is mainly determined by the initial neurological impairment which seems to depend highly on immediate hypoperfusion. Thus, in the present study, the initial early perfusion in patients with SAH was investigated with respect to their neurological outcome.

Methods: In the present series 35 patients with SAH were studied with an early CT-based perfusion measurement that was performed within the first 12 hours after initial bleeding. In all patients the mean transit time (MTT), the time to peak (TTP), the cerebral blood flow (CBF) and the cerebral blood volume (CBV) were recorded and analyzed. The results were correlated with the initial clinical status according to WFNS and the Glasgow Outcome Scale (GOS) at the time of discharge.

Results: The MTT correlated significantly with the initial WFNS scale and the GOS at time of discharge. The MTT of the right hemisphere in WFNS°I patients (n=13) was 3.2s (± 0.6), WFNS°II-III (n=8) 4.2 s (± 0.3) and in WFNS°IV-V (n=14) 4.6 s (± 0.4) whereas the MTT on the left in WFNS°I patients was 3.3 s (± 0.4), in WFNS°II-III patients 4.1 s (± 0.6) and in WFNS°IV-V patients 4.8 s (± 0.6). Further parameters did not show a significant correlation.

Conclusions: The results of the present study confirm the latest findings of our pilot series that the MTT seen in early CT-perfusion measurement correlates significantly with the initial neurological grading and the clinical outcome in patients suffering from SAH. Therefore the initial MTT can be considered as a reliable predictor of CT-perfusion.