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61. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie (DGNC) im Rahmen der Neurowoche 2010
Joint Meeting mit der Brasilianischen Gesellschaft für Neurochirurgie am 20. September 2010

Deutsche Gesellschaft für Neurochirurgie (DGNC) e. V.

21. - 25.09.2010, Mannheim

Early CT perfusion measurement after aneurysmal subarachnoid hemorrhage – A screening method to predict outcome?

Meeting Abstract

  • Hi-Jae Heiroth - Klinik für Neurochirurgie, Heinrich-Heine-Universität Düsseldorf, Deutschland
  • Marcel Kamp - Klinik für Neurochirurgie, Heinrich-Heine-Universität Düsseldorf, Deutschland
  • Bernd Turowski - Institut für Radiologie, Heinrich-Heine-Universität Düsseldorf, Deutschland
  • Hans-Jakob Steiger - Klinik für Neurochirurgie, Heinrich-Heine-Universität Düsseldorf, Deutschland
  • Daniel Hänggi - Klinik für Neurochirurgie, Heinrich-Heine-Universität Düsseldorf, Deutschland

Deutsche Gesellschaft für Neurochirurgie. 61. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie (DGNC) im Rahmen der Neurowoche 2010. Mannheim, 21.-25.09.2010. Düsseldorf: German Medical Science GMS Publishing House; 2010. DocP1846

DOI: 10.3205/10dgnc317, URN: urn:nbn:de:0183-10dgnc3179

Veröffentlicht: 16. September 2010

© 2010 Heiroth et al.
Dieser Artikel ist ein Open Access-Artikel und steht unter den Creative Commons Lizenzbedingungen (http://creativecommons.org/licenses/by-nc-nd/3.0/deed.de). Er darf vervielfältigt, verbreitet und öffentlich zugänglich gemacht werden, vorausgesetzt dass Autor und Quelle genannt werden.


Gliederung

Text

Objective: The grading of initial neurological impairment after aneurysmal subarachnoid hemorrhage (SAH) has shown to correlate significantly with patient's outcome. Immediate hypoperfusion is likely to play the major responsible role for the initial neurological status. The goal of the present study is to analyze the early perfusion in patients suffering from aneurysmal subarachnoid hemorrhage and the correlation with neurological outcome.

Methods: In the present pilot series 15 patients with SAH received an early CT based perfusion measurement that was performed within the first 12 hours after initial bleeding. In all patients the mean transit time (MTT), the time to peak (TTP), the cerebral blood flow (CBF) and the cerebral blood volume (CBV) were calculated and analyzed. The results were correlated with the initial clinical status according to WFNS and the Glasgow Outcome Scale (GOS) at time of discharge.

Results: The MTT proved to correlate significantly with the initial WFNS scale and the GOS at time of discharge. MTT of the right hemisphere in WFNS°I patients (n=5) was 3.3 s (±0.5), WFNS°II-III (n=3) 4.0 s (±0.2) and in WFNS°IV-V (n=7) 4.4 s (±0.6) whereas MTT on the left in WFNS°I patients was 3.2 s (± 0.5), in WFNS°II-III patients 4.1 s (±0.4) and in WFNS°IV-V patients 4.5 s (±0.6). Further parameters did not show significant correlation.

Conclusions: The results of the present pilot study indicates that MTT obtained from early CT-perfusion measurement correlates significantly with the initial neurological grading and the clinical outcome in patients suffering from aneurysmal subarachnoid hemorrhage. Therefore we start to analyze the predictive value of early perfusion-CT in a larger series.