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61. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie (DGNC) im Rahmen der Neurowoche 2010
Joint Meeting mit der Brasilianischen Gesellschaft für Neurochirurgie am 20. September 2010

Deutsche Gesellschaft für Neurochirurgie (DGNC) e. V.

21. - 25.09.2010, Mannheim

Surgical management of intracranial subependymomas

Meeting Abstract

  • Julia Kandenwein - Neurochirurgische Klinik der Universität Bonn, Germany
  • Azize Bostroem - Neurochirurgische Klinik der Universität Bonn, Germany
  • Johannes Schramm - Neurochirurgische Klinik der Universität Bonn, Germany
  • Matthias Simon - Neurochirurgische Klinik der Universität Bonn, Germany

Deutsche Gesellschaft für Neurochirurgie. 61. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie (DGNC) im Rahmen der Neurowoche 2010. Mannheim, 21.-25.09.2010. Düsseldorf: German Medical Science GMS Publishing House; 2010. DocP1748

DOI: 10.3205/10dgnc219, URN: urn:nbn:de:0183-10dgnc2192

Veröffentlicht: 16. September 2010

© 2010 Kandenwein et al.
Dieser Artikel ist ein Open Access-Artikel und steht unter den Creative Commons Lizenzbedingungen (http://creativecommons.org/licenses/by-nc-nd/3.0/deed.de). Er darf vervielfältigt, verbreitet und öffentlich zugänglich gemacht werden, vorausgesetzt dass Autor und Quelle genannt werden.


Gliederung

Text

Objective: Intracranial subependymomas are rare, slow-growing and non-invasive tumors. The aim of this study was to analyze short- and long-term results after surgical treatment of symptomatic intracranial subependymomas.

Methods: Between 1991 and 2007 11 patients with intracranial subependymomas had surgery in our institution. The mean age of the patients was 54.4 years (ranging from 40 to 85 years). Tumors were located in the 4th ventricle in seven patients and in the lateral ventricle in four patients. Most patients presented with symptoms related to intracranial hypertension (headache: 8, dizziness: 6, nausea: 6, gait ataxia: 4 patients), one patient with a cognitive decline and flattened affect, and one patient with a hemiparesis. Hydrocephalus was present in 6 patients, but only one needed a permanent CSF shunt.

Results: Complete removal of the tumor was possible in 8 cases. Average maximal tumor diameter was 46 mm. The Karnofsky index improved after surgery in 6 cases, remained unchanged in 4 patients, and deteriorated in 3 cases. Mean follow-up was 51.2 months. There were no true recurrences during follow-up. A second surgery was required seven years after the first operation for progression of an incompletely resected tumor in 1 case.

Conclusions: Removal of symptomatic subependymomas can be performed safely today. Prognosis is very good after a complete resection. Operations for larger lesions carry higher surgical risks, which would argue for early surgery in patients with presumed subependymoma.