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59. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie (DGNC)
3. Joint Meeting mit der Italienischen Gesellschaft für Neurochirurgie (SINch)

Deutsche Gesellschaft für Neurochirurgie (DGNC) e. V.

01. - 04.06.2008, Würzburg

Geometric analysis of the Internal Carotid Artery (ICA) in relation to aneurysms (An)

Meeting Abstract

  • corresponding author S. Bacigaluppi - Neurochirurgia e Neuroradiologia, Ospedale Niguarda Ca’ Granda, Milano
  • L. Antiga - Bioingegneria, Mario Negri, Bergamo
  • T. Passerini - MOX Politecnico, Milano
  • M. Piccinelli - Bioingegneria, Mario Negri, Bergamo
  • S. Vantini - MOX Politecnico, Milano
  • L. Sangalli - MOX Politecnico, Milano
  • A. Remuzzi - Bioingegneria, Mario Negri, Bergamo
  • P. Secchi - MOX Politecnico, Milano
  • M. Collice - Neurochirurgia e Neuroradiologia, Ospedale Niguarda Ca’ Granda, Milano
  • E. Boccardi - Neurochirurgia e Neuroradiologia, Ospedale Niguarda Ca’ Granda, Milano
  • A. Veneziani - MOX Politecnico, Milano

Deutsche Gesellschaft für Neurochirurgie. Società Italiana di Neurochirurgia. 59. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie e.V. (DGNC), 3. Joint Meeting mit der Italienischen Gesellschaft für Neurochirurgie (SINch). Würzburg, 01.-04.06.2008. Düsseldorf: German Medical Science GMS Publishing House; 2008. DocP 059

Die elektronische Version dieses Artikels ist vollständig und ist verfügbar unter: http://www.egms.de/de/meetings/dgnc2008/08dgnc328.shtml

Veröffentlicht: 30. Mai 2008

© 2008 Bacigaluppi et al.
Dieser Artikel ist ein Open Access-Artikel und steht unter den Creative Commons Lizenzbedingungen (http://creativecommons.org/licenses/by-nc-nd/3.0/deed.de). Er darf vervielf&aauml;ltigt, verbreitet und &oauml;ffentlich zug&aauml;nglich gemacht werden, vorausgesetzt dass Autor und Quelle genannt werden.


Gliederung

Text

Objective: To assess morphological differences of vessels with and without An.

Methods: 65 ICAs were reconstructed from 3D angiographies of the anterior circulation: 5 without any An, 25 with ICA An, 35 with An distal to the ICA. Diameter and curvature were evaluated statistically in relation to the presence of An. Hemodynamic computational simulations calculated wall shear stress (WSS) on some samples from each geometrical-statistical vessel class.

Results: Two ICA categories were identified: i) larger diameter and narrow bends characterized ICAs with An and also those without An ii) smaller diameter and more straight bends characterized ICAs of vessel trees where the An was located distal to the ICA. In ICAs with An, the WSS peaks were higher, particularly distributed on the internal side of the distal siphon curve and on the upper portion of the most distal ICA tract. In these examples the influence of siphon curve morphology on WSS pattern in the distal ICA tract was evident. The An itself also determines increased WSS levels on the inflow and outflow regions of the parent vessel and on eventual side vessels.

Conclusions: These initial analyses indicate the importance of the geometric features of the parent vessel for the hemodynamic impact on the wall, crucial in degenerative diseases like An and atherosclerotic plaques. If the more straight shape of the intracranial ICA in patients with An distal to the ICA is to relate to a hemodynamic problem of siphon inefficiency still needs to be determined.

Acknowledgement: Siemens Italia Medical Solutions and Politecnico Foundation for supporting the project Aneurisk