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59. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie (DGNC)
3. Joint Meeting mit der Italienischen Gesellschaft für Neurochirurgie (SINch)

Deutsche Gesellschaft für Neurochirurgie (DGNC) e. V.

01. - 04.06.2008, Würzburg

Value of high-resolution MRI of the parapontine region in the diagnosis of trigeminal neuralgia

Stellenwert der hochauflösenden MRT des Kleinhirnbrückenwinkels in der Diagnostik der Trigeminus-Neuralgie

Meeting Abstract

Suche in Medline nach

  • corresponding author D. Rasche - Neurochirurgische Klinik, Universitätsklinikum Schleswig-Holstein, Campus Lübeck
  • B. Kress - Abteilung Neuroradiologie, Krankenhaus Nordwest, Frankfurt/Main
  • D. Klase - Neurochirurgische Klinik, Universitätsklinikum Schleswig-Holstein, Campus Lübeck
  • V. M. Tronnier - Neurochirurgische Klinik, Universitätsklinikum Schleswig-Holstein, Campus Lübeck

Deutsche Gesellschaft für Neurochirurgie. Società Italiana di Neurochirurgia. 59. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie e.V. (DGNC), 3. Joint Meeting mit der Italienischen Gesellschaft für Neurochirurgie (SINch). Würzburg, 01.-04.06.2008. Düsseldorf: German Medical Science GMS Publishing House; 2008. DocMI.06.08

Die elektronische Version dieses Artikels ist vollständig und ist verfügbar unter: http://www.egms.de/de/meetings/dgnc2008/08dgnc242.shtml

Veröffentlicht: 30. Mai 2008

© 2008 Rasche et al.
Dieser Artikel ist ein Open Access-Artikel und steht unter den Creative Commons Lizenzbedingungen (http://creativecommons.org/licenses/by-nc-nd/3.0/deed.de). Er darf vervielf&aauml;ltigt, verbreitet und &oauml;ffentlich zug&aauml;nglich gemacht werden, vorausgesetzt dass Autor und Quelle genannt werden.


Gliederung

Text

Objective: The diagnosis of trigeminal neuralgia (TN) is based on clinical neurological findings and the subjective pain description of the patient. The role of MRI in the preoperative diagnosis is mainly intended for the exclusion of symptomatic neuralgia due to possible tumours or inflammation. MRI-visualization of the neurovascular contact is indifferent and in many cases also seen on the healthy side or in painfree controls. In this prospective study, additional morphological and volumetric data with high resolution MRI of the parapontine region is to be investigated and significant differences defined.

Methods: In 62 patients with unilateral TN and in 48 healthy volunteers, high-resolution MRI (1.5 T MRI-scanner) of the parapontine cistern was performed. Volumetric measurements were performed using a T2-weighted CISS-sequence (Constructive interference steady state, TE: 5.6, TR: 11.2, FoV 230, matrix 256, slice thickness: 0.9 mm, time: 5:36 min.) with coronal reconstruction. In each patient the volume of the trigeminal nerve and of the parapontine cistern as well as the course and angulations of the trigeminal nerve through the parapontine cistern was investigated intraindividually on both sides. The neuroradiologist was blinded for the diagnosis and the side of TN.

Results: Significant side differences were found for the volume of the affected nerve and also for the parapontine cistern in patients with TN (p<.01; p<.005). No significant side differences were found in the volunteer group. Measurements of the angulations of the trigeminal nerve revealed a smaller angle between the nerve and Meckel's cave on the affected side in patients (p<.005).

Conclusions: High resolution MRI of the trigeminal nerve and parapontine region offers the possibility of achieving additional morphological parameters in patients with trigeminal neuralgia. Significant side differences of the volume of the affected trigeminal nerve and parapontine cistern and the angulation of the cisternal nerve portion and Meckel's cave were found. Based on these findings, additional criteria for the identification of good candidates for microvascular decompression should be taken into consideration.