gms | German Medical Science

58. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie e. V. (DGNC)

Deutsche Gesellschaft für Neurochirurgie (DGNC) e. V.

26. bis 29.04.2007, Leipzig

Artikel

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New tools for evaluation of formation and risk of rupture of intracranial aneurysms. Aneurisk – a project in development

Neue Instrumente für die Einschätzung des Bildungs- und Bruch-Risikos von zerebralen Aneurysmen. Aneurisk – ein Projekt in Entwicklung

Meeting Abstract

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  • corresponding author S. Bacigaluppi - Università degli Studi di Milano, Clinica Neurochirurgica-Ospedale Policlinico Fondazione IRCCS
  • L. Antiga - Istituto Mario Negri, Dipartimento di Bioingegneria, Bergamo Ranica
  • P. Secchi - Dipartimento di Modellistica Matematica e Calcolo Scientifico-Politecnico di Milano
  • E. Boccardi - Divisione di Neuroradiologia-Ospedale Niguarda Ca’Granda, Milano
  • M. Piccinelli - Istituto Mario Negri, Dipartimento di Bioingegneria, Bergamo Ranica
  • S. Vantini - Dipartimento di Modellistica Matematica e Calcolo Scientifico-Politecnico di Milano
  • T. Passerini - Dipartimento di Modellistica Matematica e Calcolo Scientifico-Politecnico di Milano
  • M. L. Zavanone - Università degli Studi di Milano, Clinica Neurochirurgica-Ospedale Policlinico Fondazione IRCCS
  • S. M. Gaini - Università degli Studi di Milano, Clinica Neurochirurgica-Ospedale Policlinico Fondazione IRCCS
  • A. Veneziani - Dipartimento di Modellistica Matematica e Calcolo Scientifico-Politecnico di Milano

Deutsche Gesellschaft für Neurochirurgie. 58. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie e.V. (DGNC). Leipzig, 26.-29.04.2007. Düsseldorf: German Medical Science GMS Publishing House; 2007. DocP 068

Die elektronische Version dieses Artikels ist vollständig und ist verfügbar unter: http://www.egms.de/de/meetings/dgnc2007/07dgnc323.shtml

Veröffentlicht: 11. April 2007

© 2007 Bacigaluppi et al.
Dieser Artikel ist ein Open Access-Artikel und steht unter den Creative Commons Lizenzbedingungen (http://creativecommons.org/licenses/by-nc-nd/3.0/deed.de). Er darf vervielfältigt, verbreitet und öffentlich zugänglich gemacht werden, vorausgesetzt dass Autor und Quelle genannt werden.

Gliederung

Text

Objective: The authors present a project based on the collaboration between Neurosurgeons, Neuroradiologists and Engineers to approach the problem of cerebral aneurysms. Aim of their work is to develop new tools for understanding, estimating and treating cerebral aneurysms.

Methods: Starting from 3D angiographies in DICOM format, images are reconstructed by a segmentation technique and morphological analysis is performed by extraction of geometrical parameters and their statistical analysis. Flow simulations are performed for validation of statistical outcomes on morphology.

Results: The initial results show that the development and application of these methods is able to identify morphological characteristics of some classes of aneurysms. Analyses performed on anterior circulation vessel trees will be presented with particular attention to the role of the geometry of the parent vessel.

Conclusions: These studies stress the importance of the methodologies applied in order to gain some answers on the influence of morphology in hemodynamics and in disease development. Aim of these project is to build models and apply them to single cases in order to deliver a more individualized predictive analysis which might not only help to detect unfavourable vessel geometries but also be helpful in the development of individualized treatment strategies.