gms | German Medical Science

58. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie e. V. (DGNC)

Deutsche Gesellschaft für Neurochirurgie (DGNC) e. V.

26. bis 29.04.2007, Leipzig

Improvement of follow-up imaging of intracranial aneurysms by coregistration of 3D data sets of different angiographic imaging modalities including rDSA, MRA and CTA

Verbesserung der Verlaufsbeobachtung intrakranieller Aneurysmen durch Fusionierung von 3D-Datensätzen unterschiedlicher Untersuchungsverfahren, insbesondere von rDSA, MRA und CTA

Meeting Abstract

  • corresponding author M. Kirsch - Klinik und Poliklinik für Neurochirurgie, Medizinische Fakultät Carl Gustav Carus
  • F. Uhlemann - Institut für Biomedizinische Technik, Technische Universität Dresden
  • T. Meyer - Institut für Biomedizinische Technik, Technische Universität Dresden
  • R. Steinmeier - Klinik für Neurochirurgie, Klinikum Chemnitz
  • U. Morgenstern - Institut für Biomedizinische Technik, Technische Universität Dresden
  • G. Schackert - Klinik und Poliklinik für Neurochirurgie, Medizinische Fakultät Carl Gustav Carus

Deutsche Gesellschaft für Neurochirurgie. 58. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie e.V. (DGNC). Leipzig, 26.-29.04.2007. Düsseldorf: German Medical Science GMS Publishing House; 2007. DocSA.06.01

Die elektronische Version dieses Artikels ist vollständig und ist verfügbar unter: http://www.egms.de/de/meetings/dgnc2007/07dgnc166.shtml

Veröffentlicht: 11. April 2007

© 2007 Kirsch et al.
Dieser Artikel ist ein Open Access-Artikel und steht unter den Creative Commons Lizenzbedingungen (http://creativecommons.org/licenses/by-nc-nd/3.0/deed.de). Er darf vervielf&aauml;ltigt, verbreitet und &oauml;ffentlich zug&aauml;nglich gemacht werden, vorausgesetzt dass Autor und Quelle genannt werden.


Gliederung

Text

Objective: During the long-term follow-up of aneurysms, a variety of vascular imaging modalities are in use. The gold standard is rotational digital subtraction angiography (rDSA). However, this is not used regularly for follow-up studies. More frequently, magnetic resonance imaging (MRA) and computerized tomography angiography (CTA) is used for its ease of use and lack of side effects. However, a mix of diagnostic procedures even for the same patient is frequently encountered. The purpose of our study is to utilize sophisticated software algorithms to match, visualize and compare different 3D imaging modalities in the follow-up of treated and untreated aneurysms.

Methods: Twenty patients with one to three aneurysms were included in the study. Informed consent was obtained to utilize imaging data for complex 3D analyses and visualization. For all patients, at least two different imaging modalities were used, mainly rDSA and MRA: A database was set up containing volume data sets of all imaging procedures. Image data sets were coregistered and visualized using a commercial software system and internal developments. In addition, autostereoscopic 3D displays and a 3D mouse were used for advanced segmentation and visualization purposes.

Results: A procedure was developed which allows the import, preprocessing, segmentation, registration and visualization employing a network of various image processing modules. Despite the large amount of data, the processing and visualization of high resolution data was successfully performed on standard personal computers. Comparison of three-dimensional reconstruction of cerebral aneurysms including overlay and subtraction improved detection of subtle changes in aneurysm size and configuration over time.

Conclusions: The integration of different modalities offers high resolution analyses of conformational changes in aneurysms. Since these data sets are not used for neuronavigation, elastic transformation of the coregistered three-dimensional imaging data provides additional diagnostic support. The application of this tool is further enhanced by inclusion of morphological MR data sets for planning of endovascular and neurosurgical procedures.