gms | German Medical Science

58. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie e. V. (DGNC)

Deutsche Gesellschaft für Neurochirurgie (DGNC) e. V.

26. bis 29.04.2007, Leipzig

Anterior clinoid meningiomas: Outcome in a consecutive series of 72 patients treated by microsurgery

Vordere Clinoid-Fortsatz-Meningeome: Mikrochirurgische Ergebnisse in einem konsekutiven Kollektiv von 72 Patienten

Meeting Abstract

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  • corresponding author H. Bassiouni - Neurochirurgische Klinik, Universitätsklinikum Essen
  • S. Asgari - Neurochirurgische Klinik, Universitätsklinikum Essen
  • D. Stolke - Neurochirurgische Klinik, Universitätsklinikum Essen

Deutsche Gesellschaft für Neurochirurgie. 58. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie e.V. (DGNC). Leipzig, 26.-29.04.2007. Düsseldorf: German Medical Science GMS Publishing House; 2007. DocDO.04.01

Die elektronische Version dieses Artikels ist vollständig und ist verfügbar unter:

Veröffentlicht: 11. April 2007

© 2007 Bassiouni et al.
Dieser Artikel ist ein Open Access-Artikel und steht unter den Creative Commons Lizenzbedingungen ( Er darf vervielfältigt, verbreitet und öffentlich zugänglich gemacht werden, vorausgesetzt dass Autor und Quelle genannt werden.



Objective: We conducted a retrospective analysis in a consecutive series of patients treated by microsurgery for an anterior clinoid meningioma with regard to long-term follow-up results.

Methods: Clinical, radiological and surgical data were reviewed in a consecutive series of 72 patients treated with microsurgery for an anterior clinoid meningioma in the period from June 1987 till June 2005.

Results: The main presenting symptoms in the 64 women and 8 men (mean age 55 yrs, range 24 to 74 yrs) were visual impairment in 59% and headache in 34% of the patients. Mean duration of preoperative symptoms prior to hospital admission was 19 months, with a wide range from 10 days to 11 years. Ophthalmological examination revealed diminished visual acuity in 63% and a visual field deficit in 28% of the cases. Preoperative magnetic resonance imaging (MRI) demonstrated tumor extension into the cavernous sinus in 45% of patients. Extent of tumor resection, usually via the pterional approach, was grade I in 4% and grade II in 58% of the cases according to Simpson’s classification system. The intracavernous tumor portion was left in situ in 37% of cases (grade IV). Impaired visual acuity improved postoperatively in 47%, remained unchanged in 47% and deteriorated in 6% of patients. The surgical mortality and the permanent morbidity rates were 3% and 23%, respectively. The Karnofsky performance score improved from 84 before operation to 88 after surgery. After a mean follow-up period of 7.3 years (range 1.5 yrs to 17 yrs) with clinical and MRI examination, we observed a tumor recurrence in 16% after a Simpson grade I and II removal and clinical progression of known residual tumor in a further 38% of patients.

Conclusions: Although acceptable early results can be achieved in this challenging skull base meningioma group with microsurgical resection, long-term functional outcome is less favourable due to a high recurrence rate after an apparently complete resection or progression of residual tumor due to the involvement of the cavernous sinus.