gms | German Medical Science

56. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie e. V. (DGNC)
3èmes journées françaises de Neurochirurgie (SFNC)

Deutsche Gesellschaft für Neurochirurgie e. V.
Société Française de Neurochirurgie

07. bis 11.05.2005, Strasbourg

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Treatment and results in Cushing disease with normal magnetic resonance imaging

Meeting Abstract

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  • corresponding author M. Aitbachir - Department of Neurosurgery, BABELOUED Hospital Algiers, Algeria
  • A. Morsli - Department of Neurosurgery, BABELOUED Hospital Algiers, Algeria
  • L. Berchiche - Department of Neurosurgery, BABELOUED Hospital Algiers, Algeria
  • B. Yacoubi - Department of Neurosurgery, BABELOUED Hospital Algiers, Algeria
  • A. Sidisaid - Department of Neurosurgery, BABELOUED Hospital Algiers, Algeria
  • T. Benbouzid - Department of Neurosurgery, BABELOUED Hospital Algiers, Algeria

Deutsche Gesellschaft für Neurochirurgie. Société Française de Neurochirurgie. 56. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie e.V. (DGNC), 3èmes journées françaises de Neurochirurgie (SFNC). Strasbourg, 07.-11.05.2005. Düsseldorf, Köln: German Medical Science; 2005. DocP123

Die elektronische Version dieses Artikels ist vollständig und ist verfügbar unter: http://www.egms.de/de/meetings/dgnc2005/05dgnc0391.shtml

Veröffentlicht: 4. Mai 2005

© 2005 Aitbachir et al.
Dieser Artikel ist ein Open Access-Artikel und steht unter den Creative Commons Lizenzbedingungen (http://creativecommons.org/licenses/by-nc-nd/3.0/deed.de). Er darf vervielfältigt, verbreitet und öffentlich zugänglich gemacht werden, vorausgesetzt dass Autor und Quelle genannt werden.

Gliederung

Text

Objective

Cushing disease without any pituitary adenoma visible on MRI is a challenge for both the neurosurgeon and the biologist; we report our experience concerning a subgroup of six patients operated on for this pathology, extracted from a total of 23 patients admitted from Cushing disease treated in our departement over the last four years period.

Methods

We reviewed retropectively a series of 23 patients who underwent transphenoidal surgery; six patients fullfiled the criteria for the study; normal MRI of the pituitary area, no previoud surgery and aperated by sub labial transphénoidal. The age average of the patients was 35 years, there was female preponderance (5 womens/1man) .All patients had clinically severe disease and underwent a preopérative IPSS.

Results

Intra operatively, an adenoma was found in four cases in whom a selective removal of the tumors was achieved; the two remaining cases underwent an hemihypophysectomy on the side of abnormal IPSS. After on average follow up of 20 months all of patients are in remission.

Conclusions

Cushing disease in patients with a normal MRI can succesfuly treated by surgery, inferior petrosal sinus sampling (IPSS) can be helpful in localizing the adenoma. Complication was especially cerebro spinal fluid fistulas.