gms | German Medical Science

56. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie e. V. (DGNC)
3èmes journées françaises de Neurochirurgie (SFNC)

Deutsche Gesellschaft für Neurochirurgie e. V.
Société Française de Neurochirurgie

07. bis 11.05.2005, Strasbourg

Radiotherapy or imaging follow-up after surgery of non-functioning pituitary adenomas? A retrospective study of 45 cases

Meeting Abstract

  • corresponding author S. Litrico - Departement of Neurosurgery, Nice, France
  • E. Bozzolo - Departement of Neurosurgery, Nice, France
  • F. Fauchon - Department of Radiotherapy, Nice, France
  • J. L. Sadoul - Departement of Neurosurgery, Nice, France
  • P. Paquis - Departement of Neurosurgery, Nice, France

Deutsche Gesellschaft für Neurochirurgie. Société Française de Neurochirurgie. 56. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie e.V. (DGNC), 3èmes journées françaises de Neurochirurgie (SFNC). Strasbourg, 07.-11.05.2005. Düsseldorf, Köln: German Medical Science; 2005. Doc11.05.-02.03

Die elektronische Version dieses Artikels ist vollständig und ist verfügbar unter: http://www.egms.de/de/meetings/dgnc2005/05dgnc0184.shtml

Veröffentlicht: 4. Mai 2005

© 2005 Litrico et al.
Dieser Artikel ist ein Open Access-Artikel und steht unter den Creative Commons Lizenzbedingungen (http://creativecommons.org/licenses/by-nc-nd/3.0/deed.de). Er darf vervielf&aauml;ltigt, verbreitet und &oauml;ffentlich zug&aauml;nglich gemacht werden, vorausgesetzt dass Autor und Quelle genannt werden.


Gliederung

Text

Objective

Post operative radiotherapy is often advocated as an effective treatment modality for non-functioning pituitary adenomas with postoperative residue. However, this treatment may have some side-effects and this systematic attitude is now controversial. The aim is to evaluate if there is a significant difference between non-functioning adenomas treated by postoperative radiotherapy and those only followed with recurrent imaging.

Methods

We study a retrospective series of 45 cases of non-functioning adenomas treated by surgery between 1991 and 2001. 35 patients had tumoral residue after surgery. 10 patients were treated by radiotherapy, 25 patients had a recurrent follow-up with MRI. We compare the rate of regrowth for each group and seek side-effects of radiotherapy.

Results

Tumor regrowth occurred in one case for the patients treated by radiotherapy. In the subgroup with MRI follow-up, we note two cases of long term recurrence. There is no significant difference between these two groups. For three patients treated by radiotherapy, we notice occurrence of side-effects: a transitory visual worsening, a mucous dryness syndrome, and a lacrymal hypersecretion.

Conclusions

Radiotherapy does not seem to bring of benefit in the postoperative strategy of non functioning pituitary adenomas. With these results, we suggest that MRI follow-up without systematic radiotherapy is the best strategy after surgery of non-functioning pituitary adenomas.