gms | German Medical Science

129. Kongress der Deutschen Gesellschaft für Chirurgie

Deutsche Gesellschaft für Chirurgie

24.04. - 27.04.2012, Berlin

ADEPT®-solution in the prophylaxis and therapy of ileus in children – case reports

Meeting Abstract

  • Carsten Müller - Klinik für Kinderchirurgie, Universitätsmedizin, Greifswald
  • David Großmann - Klinik für Kinderchirurgie, Universitätsmedizin, Greifswald
  • Nils-Olaf Hübner - Institut für Hygiene und Umweltmedizin, Universitätsmedizin, Greifswald
  • Axel Kramer - Universitätsmedizin Greifswald, Institut für Hygiene und Umweltmedizin, Greifswald
  • Winfried Barthlen - Klinik für Kinderchirurgie, Universitätsmedizin, Greifswald

Deutsche Gesellschaft für Chirurgie. 129. Kongress der Deutschen Gesellschaft für Chirurgie. Berlin, 24.-27.04.2012. Düsseldorf: German Medical Science GMS Publishing House; 2012. Doc12dgch396

doi: 10.3205/12dgch396, urn:nbn:de:0183-12dgch3967

Veröffentlicht: 23. April 2012

© 2012 Müller et al.
Dieser Artikel ist ein Open Access-Artikel und steht unter den Creative Commons Lizenzbedingungen ( Er darf vervielfältigt, verbreitet und öffentlich zugänglich gemacht werden, vorausgesetzt dass Autor und Quelle genannt werden.



Introduction: Ileus prophylaxis and therapy at an early age is a special challenge. Commonly used inner splintings, for example according to SAUER by means of an inserted probe via caecostomy only allow a meander-like adherence of the intestines with an immolation of the appendix.

Especially relapse operations with congenital diseases or also preceding inflammatory processes in the neonatal period can be complicated through adhesions and strangulations. So far there have not been any reports in paediatric surgery on ADEPT® (4%-Icodextrin solution, Baxter company) – a successfully employed agent in randomized studies in general surgery and gynaecology. We want to show first successful treatments.

Material and methods: In the quantitative suspension test ADEPT® showed no antibacterial effect but also no relevant growrth stimulation in comparison to the controls. However, this is not to be considered as relevant. Therefore there is no sign that ADEPT® is a culture medium for the examined pathogenic agents. Thus it is also usable as a means for hydroflotation with septic diseases.

Results: We report on 15 children from neonate to adolescent, with whom we used ADEPT® due to the intraoperative diagnosis like distinctive adhesions, recurrent adhesions but also severest post-inflammatory changes, respectively. During the treatment we varied between lavage alone, temporary instillation and temporally unlimited instillation. All patients primarily showed uncomplicated courses and have not needed recurrent operations so far.

Conclusion: From our experience ADEPT® is suitable for the adhesion prophylaxis also in children.