gms | German Medical Science

128. Kongress der Deutschen Gesellschaft für Chirurgie

Deutsche Gesellschaft für Chirurgie

03.05. - 06.05.2011, München

The MR-visible-Mesh as IPOM in rabbits: First in-vivo imaging of mesh ingrowth und delineation to its surrounding structures

Meeting Abstract

  • Jens Otto - Universitätsklinik der RWTH-Aachen, Chirurgische Klinik, Aachen
  • Nicolas Kühnert - Universitätsklinik der RWTH-Aachen, Chirurgische Klinik, Aachen
  • Nils Krämer - Universitätsklinik der RWTH-Aachen, Klinik für Radiologische Diagnostik, Aachen
  • Hank Donker - Universitätsklinik der RWTH-Aachen, Klinik für Radiologische Diagnostik, Aachen
  • Christiane Kuhl - Universitätsklinik der RWTH-Aachen, Klinik für Radiologische Diagnostik, Aachen
  • Iona Slabu - Helmholtz-Institut für Biomedizinische Technik, Lehrstuhl für Angewandte Medizintechnik, Aachen
  • Michael Hodenius - Helmholtz-Institut für Biomedizinische Technik, Lehrstuhl für Angewandte Medizintechnik, Aachen
  • Uwe Klinge - Universitätsklinik der RWTH-Aachen, Chirurgische Klinik, Aachen

Deutsche Gesellschaft für Chirurgie. 128. Kongress der Deutschen Gesellschaft für Chirurgie. München, 03.-06.05.2011. Düsseldorf: German Medical Science GMS Publishing House; 2011. Doc11dgch172

DOI: 10.3205/11dgch172, URN: urn:nbn:de:0183-11dgch1725

Veröffentlicht: 20. Mai 2011

© 2011 Otto et al.
Dieser Artikel ist ein Open Access-Artikel und steht unter den Creative Commons Lizenzbedingungen (http://creativecommons.org/licenses/by-nc-nd/3.0/deed.de). Er darf vervielfältigt, verbreitet und öffentlich zugänglich gemacht werden, vorausgesetzt dass Autor und Quelle genannt werden.


Gliederung

Text

Introduction: Implantation of textile meshes can cause severe complications like migration, erossion, shrinkage, deformation and fistula formation. In some of these cases the indication for surgical correction is beyond despute, but often “only” funtional problems or unspecific discomfort may be suspected. In these cases the required procedere is not clear.

Until now the conventional diagnostic is limited because X-ray, ultrasound, CT and MRI usually fail to visualize the mesh device. Only in exceptional cases, if the mesh is surrounded by fluids or fat, the structure of the mesh can be delineated.

Materials and methods: After we could establish a possibility to produce and to visualize a MR-visible mesh melting down MR-contrast medium into PVDF, we could now present the first trial of imaging the mesh ingrowth und its delineation to surrounding structures.

Therefor we implanted MR visible MeshInSight (6x4 cm) in IPOM-position in 10 rabbits laparoscopically. After 4 and 12 weeks we explanted 5 animals in each case. The histological analysis and the macroscopic results of adhesion and deformation were compared to the findings of MR investigations, which were done repeatedly during the whole period of examination.

Results: In the underlaying study in a living animal we could evaluate a mesh ingrowth in terms of position, deformation and delineation to its surrounding structures for the first time.

The use of such a visible mesh will be helpful for decision whether a revison operation of the mesh is necessary (explantation, refixation, implantation of a bigger mesh…) or not (in case of not mesh-related current complaints). Furthermore the visible mesh then could be useful to plan a revision.

Conclusion: This work is supported by the German Federal Mininstry of Education and Research (BMBF 01EZ 0849).