gms | German Medical Science

27. Deutscher Krebskongress

Deutsche Krebsgesellschaft e. V.

22. - 26.03.2006, Berlin

Cell Cycle, Apoptosis, Angiogenesis

Meeting Abstract (OP485)

Guanylate Binding Protein-1 (GBP-1) Expression Characterizes Colorectal Carcinomas with High Intrinsic Anti-Angiogenic Activity and Correlates with Prolonged Survival in Progressed Stages

Naschberger E, Croner RS, Papadopoulos T, Merkel S, Hohenberger W, Stürzl M
Meeting Abstract (OP486)

Effects of a combined treatment with mTOR inhibitor RAD001 and tamoxifen in vitro on growth and apoptosis of human cancer cells

Pfeiler G, Ortmann O, Treeck O
Meeting Abstract (OP487)

ITF-2 is a candidate tumor suppressor gene located on chromosome 18q21

Herbst A, Bommer G, Behrens A, Jäger C, Brabletz T, Göke B, Kolligs FT
Meeting Abstract (OP488)

Influence of mismatch repair status on the response of colon carcinoma cells to the topoisomerase I inhibitor SN-38*

Bhonde M, Hanski ML, Zeitz M, Hanski C
Meeting Abstract (OP489)

Expression profile of TRAIL and DR5 splice variants in human renal cell carcinoma

Göbel N, Krieg A, Ramp U, Wethkamp N, Kempf T, Gabbert HE, Mahotka C
Meeting Abstract (OP490)

Studies on p53, BAX, and Bcl-2 Protein Expression in Stage III (UICC) Colon Cancer Treated by Adjuvant Chemotherapy: Major Prognostic Impact of Proapoptotic BAX Pronounced by Intact p53

Nehls O, Okech T, Hsieh CJ, Sarbia M, Borchard F, Gruenagel HH, Gaco V, Hass HG, Arkenau HT, Hartmann JT, Porschen R, Gregor M, Klump B
Meeting Abstract (OP491)

The predictive value of genes of the TGFß1 pathway in multimodal treated patients with esophageal squamous cell carcinoma

Brücher B, Pühringer-Oppermann F, Molls M, Siewert JR, Sarbia M
Meeting Abstract (PO492)

Interaction of Sp1 and Sp3 with an upstream GC-rich enhancer is essential for the transcriptional control of the human Angiopoietin-2 Gene (ang-2) in Endothelial Cells

Wenke J, Hertel J, Strowski MZ, Höcker M
Meeting Abstract (PO493)

cDNA Microarray analysis of apoptotic effects of different chemotherapeutics in human fibrosarcoma cells

Daigeler A, Kuhnen C, Müller O, Klein-Hitpass L, Steinau HU, Lehnhardt M
Meeting Abstract (PO494)

Combinatory Effects of HHV-8-Encoded Proteins: High Throughput Analysis for the Discovery of Pathogenic Factors in the Development of Kaposi’s Sarcoma

Konrad A, Wies E, Thurau M, Leubert R, Bauer S, Schulz TF, Hohenberger W, Naschberger E, Neipel F, Stürzl M
Meeting Abstract (PO495)

Novel strategies to target the survivin pathway in cancer – interference with nuclear export prevents the tumor promoting activites of survivin

Knauer S, Knauer SK, Krämer OH, Knösel T, Engels K, Rödel F, Brieger J, Mann W, Habtemichael N, Petersen I, Heinzel T, Stauber R
Meeting Abstract (PO496)

The CK1delta/epsilon specific inhibitor IC261 abolishes the growth of pancreatic tumor cells and sensitizes pancreatic tumor cells against CD95-mediated apoptosis

Knippschild U, Bohm B, Huber N, Giamas G, Eismann T, Hillenbrand A, Henne-Bruns D, Kalthoff H, Trauzold A, Brockschmidt C
Meeting Abstract (PO497)

Pylymorphisms of the pKi-67 Promoter and their Biologic Relevance

Duchrow M, Maaser D, Wehrstedt A, Bruch HP, Broll R
Meeting Abstract (PO498)

Histone deacetylase inhibitors interfere with angiogenesis by decreasing endothelial VEGFR2 protein half-life in part via a CBL dependent mechanism

Meissner M, Hrgovic I, Kaufmann R, Gille J
Meeting Abstract (PO499)

Blockade of heat-shock protein 90 (Hsp90) disrupts insulin-like growth factor-I receptor (IGF-IR) signaling in human pancreatic cancer cells and inhibits tumor cell migration in vitro

Lang SA, Klein D, Schlitt HJ, Geissler EK, Stöltzing O
Meeting Abstract (PO500)

TRAIL-beta and TRAIL-gamma: first clues for their role in tumor biology of gastric carcinomas

Krieg A, Göbel N, Krieg T, Schulte am Esch 2nd J, Peiper M, Ramp U, Knoefel WT, Gabbert HE, Mahotka C
Meeting Abstract (PO501)

TRAIL-R4-beta: A novel alternative splice variant of the TRAIL-receptor 4 with loss of the cystein rich domain CRD1

Krieg A, Schulte am Esch 2nd J, Hosch SB, Ramp U, Knoefel WT, Gabbert HE, Mahotka C
Meeting Abstract (PO502)

The TRAF3 binding site of human molluscipox virus FLIP molecule MC159 is critical for its capacity to inhibit Fas-induced apoptosis

Thurau M, Everett H, Tapernoux M, Tschopp J, Thome M
Meeting Abstract (PO503)

DNA damage-induced expression of p53 suppresses mitotic checkpoint kinase hMps1: the lack of this suppression in p53mut cells contributes to apoptosis

Bhonde M, Hanski ML, Budczies J, Cao M, Gillissen B, Simonetta F, Scherubl H, Truss M, Hagemeier C, Daniel PT, Zeitz M, Hanski C
Meeting Abstract (PO504)

Increased cytotoxicity of ionizing radiation in combination with the membrane targeted apoptosis modulator erucylphosphocholine involves downregulation of PKB/Akt mediated survival signaling and induction of apoptosis

Handrick R, Rübel A, Eibl H, Belka C, Jendrossek V
Meeting Abstract (PO505)

hGBP-1 inhibits UV induced nuclear accumulation of p53 tumor suppressor in human umbilical vein endothelial cells

Weinländer K, Pogoda K, Thurau M, Hohenberger W, Stürzl M
Meeting Abstract (PO506)

Apoptotic effect of receptor tyrosine kinase inhibitors on human cancer cell lines with different PTEN status

Horn F, Ortmann O, Treeck O
Meeting Abstract (PO507)

Inhibition of in vitro and in vivo angiogenesis and tumour growth by a novel a5b1 inhibitor

Dietz C, Soulaiman M, Karakas E, Hennig S, Zahn G, Stragies R, Celik I
Meeting Abstract (PO508)

Inhibition of Caspase-3 and –9 by Survivin and its splice variants Survivin-ΔEx3, Survivin-2B and Survivin-3B

Wagener J, Gabbert HE, Mahotka C
Meeting Abstract (PO509)

Protein kinase A (PKA) plays an important role in modulating the activity of CK1 delta in vitro and in vivo

Knippschild U, Shoshiashvilli L, Grothey A, Henne-Bruns D, Giamas G
Meeting Abstract (PO510)

Effects of Doxorubicin on human Liposarcoma – a gene expression study

Daigeler A, Kuhnen C, Müller O, Klein-Hitpass L, Steinau HU, Lehnhardt M
Meeting Abstract (PO511)

Cell death is not effected by the apoptosis enhancer Daxx in drug and CD95-mediated apoptosis in renal cell carcinoma

Mahotka C, Wethkamp N, Reinecke P, Gabbert HE
Meeting Abstract (PE512)

The role of MSH2 for the repair of UV-B-induced DNA-double-strand-breaks

Seifert M, Scherer S, Edelmann W, Löbrich M, Meineke V, Tilgen W, Reichrath J
Meeting Abstract (PE513)

Vitamin D analogues modulate DNA repair following UV- and ionizing radiation

Tremezaygues L, Seifert M, Meineke V, Löbrich M, Tilgen W, Reichrath J